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N-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled Receptor
A highly crystallizable T4 lysozyme (T4L) was fused to the N-terminus of the β(2) adrenergic receptor (β(2)AR), a G-protein coupled receptor (GPCR) for catecholamines. We demonstrate that the N-terminal fused T4L is sufficiently rigid relative to the receptor to facilitate crystallogenesis without t...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464249/ https://ncbi.nlm.nih.gov/pubmed/23056231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046039 |
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