Tolerance of human MSH2(+/−) lymphoblastoid cells to the methylating agent temozolomide
Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic fe...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121136498 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|
