Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

Endometrial cancer is the most common gynecologic malignancy in the United States and the most frequent extracolonic tumor in hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC patients have inherited defects in DNA mismatch repair and the microsatellite instability (MSI) tumor phenotype. Spor...

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Detalhes bibliográficos
Main Authors: Goodfellow, Paul J., Buttin, Barbara M., Herzog, Thomas J., Rader, Janet S., Gibb, Randall K., Swisher, Elizabeth, Look, Katherine, Walls, Ken C., Fan, Ming-Yu, Mutch, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC156300/
https://ncbi.nlm.nih.gov/pubmed/12732731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1030231100
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