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Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

Endometrial cancer is the most common gynecologic malignancy in the United States and the most frequent extracolonic tumor in hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC patients have inherited defects in DNA mismatch repair and the microsatellite instability (MSI) tumor phenotype. Spor...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Goodfellow, Paul J., Buttin, Barbara M., Herzog, Thomas J., Rader, Janet S., Gibb, Randall K., Swisher, Elizabeth, Look, Katherine, Walls, Ken C., Fan, Ming-Yu, Mutch, David G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2003
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12732731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1030231100
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