Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

Endometrial cancer is the most common gynecologic malignancy in the United States and the most frequent extracolonic tumor in hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC patients have inherited defects in DNA mismatch repair and the microsatellite instability (MSI) tumor phenotype. Spor...

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Detaylı Bibliyografya
Asıl Yazarlar: Goodfellow, Paul J., Buttin, Barbara M., Herzog, Thomas J., Rader, Janet S., Gibb, Randall K., Swisher, Elizabeth, Look, Katherine, Walls, Ken C., Fan, Ming-Yu, Mutch, David G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC156300/
https://ncbi.nlm.nih.gov/pubmed/12732731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1030231100
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