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Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers

Endometrial cancer is the most common gynecologic malignancy in the United States and the most frequent extracolonic tumor in hereditary nonpolyposis colorectal cancer (HNPCC). HNPCC patients have inherited defects in DNA mismatch repair and the microsatellite instability (MSI) tumor phenotype. Spor...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Goodfellow, Paul J., Buttin, Barbara M., Herzog, Thomas J., Rader, Janet S., Gibb, Randall K., Swisher, Elizabeth, Look, Katherine, Walls, Ken C., Fan, Ming-Yu, Mutch, David G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12732731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1030231100
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