Tolerance of human MSH2(+/−) lymphoblastoid cells to the methylating agent temozolomide

Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic fe...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Marra, Giancarlo, D'Atri, Stefania, Corti, Chantal, Bonmassar, Laura, Cattaruzza, Maria Sofia, Schweizer, Pascal, Heinimann, Karl, Bartosova, Zdena, Nyström-Lahti, Minna, Jiricny, Josef
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121136498
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!