Tolerance of human MSH2(+/−) lymphoblastoid cells to the methylating agent temozolomide
Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic fe...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
2001
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121136498 |
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