Tolerance of human MSH2(+/−) lymphoblastoid cells to the methylating agent temozolomide

Members of hereditary nonpolyposis colon cancer (HNPCC) families harboring heterozygous germline mutations in the DNA mismatch repair genes hMSH2 or hMLH1 present with tumors generally two to three decades earlier than individuals with nonfamilial sporadic colon cancer. We searched for phenotypic fe...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Marra, Giancarlo, D'Atri, Stefania, Corti, Chantal, Bonmassar, Laura, Cattaruzza, Maria Sofia, Schweizer, Pascal, Heinimann, Karl, Bartosova, Zdena, Nyström-Lahti, Minna, Jiricny, Josef
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2001
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416201/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121136498
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