PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

NETosis, the process wherein neutrophils release highly decondensed chromatin called neutrophil extracellular traps (NETs), has gained much attention as an alternative means of killing bacteria. In vivo, NETs are induced by bacteria and pro-inflammatory cytokines. We have reported that peptidylargin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Leshner, Marc, Wang, Shu, Lewis, Carrie, Zheng, Han, Chen, Xiangyun Amy, Santy, Lorraine, Wang, Yanming
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2012
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463874/
https://ncbi.nlm.nih.gov/pubmed/23060885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00307
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