PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

Neutrophils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs). We previously reported that histone hypercitrullination catalyzed by peptidylarginine deiminase 4 (PAD4) correlates with chromatin decondensation during NET formation....

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Detalhes bibliográficos
Main Authors: Li, Pingxin, Li, Ming, Lindberg, Michael R., Kennett, Mary J., Xiong, Na, Wang, Yanming
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931169/
https://ncbi.nlm.nih.gov/pubmed/20733033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100239
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