PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

Neutrophils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs). We previously reported that histone hypercitrullination catalyzed by peptidylarginine deiminase 4 (PAD4) correlates with chromatin decondensation during NET formation....

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Bibliographische Detailangaben
Hauptverfasser: Li, Pingxin, Li, Ming, Lindberg, Michael R., Kennett, Mary J., Xiong, Na, Wang, Yanming
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931169/
https://ncbi.nlm.nih.gov/pubmed/20733033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100239
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