PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

Neutrophils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs). We previously reported that histone hypercitrullination catalyzed by peptidylarginine deiminase 4 (PAD4) correlates with chromatin decondensation during NET formation....

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Bibliografische gegevens
Hoofdauteurs: Li, Pingxin, Li, Ming, Lindberg, Michael R., Kennett, Mary J., Xiong, Na, Wang, Yanming
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2010
Onderwerpen:
Brief Definitive Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931169/
https://ncbi.nlm.nih.gov/pubmed/20733033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100239
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