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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

Neutrophils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs). We previously reported that histone hypercitrullination catalyzed by peptidylarginine deiminase 4 (PAD4) correlates with chromatin decondensation during NET formation....

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Main Authors: Li, Pingxin, Li, Ming, Lindberg, Michael R., Kennett, Mary J., Xiong, Na, Wang, Yanming
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931169/
https://ncbi.nlm.nih.gov/pubmed/20733033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100239
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