Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

Peripheral blood neutrophils form highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs), that have been implicated in innate immune response to bacterial infection. Neutrophils express high levels of peptidylarginine deiminase 4 (PAD4), which catalyzes histone citrull...

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Autors principals: Wang, Yanming, Li, Ming, Stadler, Sonja, Correll, Sarah, Li, Pingxin, Wang, Danchen, Hayama, Ryo, Leonelli, Lauriebeth, Han, Hyunsil, Grigoryev, Sergei A., Allis, C. David, Coonrod, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2009
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654299/
https://ncbi.nlm.nih.gov/pubmed/19153223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806072
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