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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
Peripheral blood neutrophils form highly decondensed chromatin structures, termed neutrophil extracellular traps (NETs), that have been implicated in innate immune response to bacterial infection. Neutrophils express high levels of peptidylarginine deiminase 4 (PAD4), which catalyzes histone citrull...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654299/ https://ncbi.nlm.nih.gov/pubmed/19153223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806072 |
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