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Chromatin targeting of nuclear pore proteins induces chromatin decondensation

Nuclear pore complexes have emerged in recent years as chromatin-binding nuclear scaffolds, able to influence target gene expression. However, how nucleoporins (Nups) exert this control remains poorly understood. Here we show that ectopically tethering Drosophila Nups, especially Sec13, to chromatin...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Kuhn, Terra M., Pascual-Garcia, Pau, Gozalo, Alejandro, Little, Shawn C., Capelson, Maya
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719443/
https://ncbi.nlm.nih.gov/pubmed/31366666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807139
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