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Chromatin targeting of nuclear pore proteins induces chromatin decondensation

Nuclear pore complexes have emerged in recent years as chromatin-binding nuclear scaffolds, able to influence target gene expression. However, how nucleoporins (Nups) exert this control remains poorly understood. Here we show that ectopically tethering Drosophila Nups, especially Sec13, to chromatin...

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Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Kuhn, Terra M., Pascual-Garcia, Pau, Gozalo, Alejandro, Little, Shawn C., Capelson, Maya
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719443/
https://ncbi.nlm.nih.gov/pubmed/31366666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807139
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