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Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

Neutrophils respond to various stimuli by decondensing and releasing nuclear chromatin characterized by citrullinated histones as neutrophil extracellular traps (NETs). This achieves pathogen immobilization or initiation of thrombosis, yet the molecular mechanisms of NET formation remain elusive. Pe...

詳細記述

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書誌詳細
出版年:Front Immunol
主要な著者: Gößwein, Stefanie, Lindemann, Aylin, Mahajan, Aparna, Maueröder, Christian, Martini, Eva, Patankar, Jay, Schett, Georg, Becker, Christoph, Wirtz, Stefan, Naumann-Bartsch, Nora, Bianchi, Marco E., Greer, Peter A., Lochnit, Günter, Herrmann, Martin, Neurath, Markus F., Leppkes, Moritz
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817590/
https://ncbi.nlm.nih.gov/pubmed/31695698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02481
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