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Human Liver Methionine Cycle: MAT1A and GNMT Gene Resequencing, Functional Genomics, and Hepatic Genotype-Phenotype Correlation

The “methionine cycle” plays a critical role in the regulation of concentrations of (S)-adenosylmethionine (AdoMet), the major biological methyl donor. We set out to study sequence variation in genes encoding the enzyme that synthesizes AdoMet in liver, methionine adenosyltransferase 1A (MAT1A) and...

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Xehetasun bibliografikoak
Egile Nagusiak: Ji, Yuan, Nordgren, Kendra K. S., Chai, Yubo, Hebbring, Scott J., Jenkins, Gregory D., Abo, Ryan P., Peng, Yi, Pelleymounter, Linda L., Moon, Irene, Eckloff, Bruce W., Chai, Xiaoshan, Zhang, Jianping, Fridley, Brooke L., Yee, Vivien C., Wieben, Eric D., Weinshilboum, Richard M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463826/
https://ncbi.nlm.nih.gov/pubmed/22807109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.046953
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