Methionine Adenosyltransferase 2A/2B and Methylation: Gene Sequence Variation and Functional Genomics

Methionine adenosyltransferase (MAT) catalyzes the synthesis of S-adenosylmethionine, the major biological methyl donor. MAT1A and MAT2A encode two distinct MAT isoforms in mammals. MAT2A is expressed in nonhepatic tissues, whereas MAT1A is expressed in the liver. A third gene, MAT2B, encodes a MAT2...

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Autors principals: Nordgren, Kendra K. S., Peng, Yi, Pelleymounter, Linda L., Moon, Irene, Abo, Ryan, Feng, Qiping, Eckloff, Bruce, Yee, Vivien C., Wieben, Eric, Weinshilboum, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198898/
https://ncbi.nlm.nih.gov/pubmed/21813468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.040857
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