Proteasome β Subunit Pharmacogenomics: Gene Resequencing and Functional Genomics

PURPOSE: The proteasome is a multisubunit cellular organelle that functions as a nonlysosomal threonine protease. Proteasomes play a critical role in the degradation of proteins, regulating a variety of cellular processes, and they are also the target for antineoplastic proteasome inhibitors. Geneti...

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Detalhes bibliográficos
Main Authors: Wang, Liewei, Kumar, Shaji, Fridley, Brooke L., Kalari, Krishna R., Moon, Irene, Pelleymounter, Linda L., Hildebrandt, Michelle A.T., Batzler, Anthony, Eckloff, Bruce W., Wieben, Eric D., Greipp, Philip R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778274/
https://ncbi.nlm.nih.gov/pubmed/18519783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5150
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