Gemcitabine metabolic pathway genetic polymorphisms and response in non-small cell lung cancer patients

BACKGROUND AND OBJECTIVE: Gemcitabine is widely used to treat non-small cell lung cancer (NSCLC). To assess the pharmacogenomic effects of the entire gemcitabine metabolic pathway, we genotyped SNPs within the 17 pathway genes using DNA samples from NSCLC patients treated with gemcitabine to determi...

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Detalhes bibliográficos
Main Authors: Li, Liang, Schaid, Daniel J., Fridley, Brooke L., Kalari, Krishna R., Jenkins, Gregory D., Abo, Ryan P., Batzler, Anthony, Moon, Irene, Pelleymounter, Linda, Eckloff, Bruce W., Wieben, Eric D., Sun, Zhifu, Yang, Ping, Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259218/
https://ncbi.nlm.nih.gov/pubmed/22173087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834dd7e2
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