Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines

BACKGROUND: Two cytidine analogues, gemcitabine and cytosine arabinoside (AraC), are widely used in the treatment of a variety of cancers with a large individual variation in response. To identify potential genetic biomarkers associated with response to these two drugs, we used a human lymphoblastoi...

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Detalhes bibliográficos
Main Authors: Li, Liang, Fridley, Brooke L, Kalari, Krishna, Niu, Nifang, Jenkins, Gregory, Batzler, Anthony, Abo, Ryan P, Schaid, Daniel, Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930546/
https://ncbi.nlm.nih.gov/pubmed/24483146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-93
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