Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs)

Homoharringtonine (HHT) has been widely used in China to treat patients with acute and chronic myeloid leukemia for decades. Since response to HHT varies among patients, our study aimed to identify biomarkers that might influence the response to HHT using a panel of various human lymphoblastoid cell...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Tong, Yin, Niu, Nifang, Jenkins, Gregory, Batzler, Anthony, Li, Liang, Kalari, Krishna R., Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292778/
https://ncbi.nlm.nih.gov/pubmed/25628645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00465
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