Binding of a tritiated inverse agonist to cannabinoid CB(1) receptors is increased in patients with schizophrenia

This study sought to determine whether cannabinoid-1 (CB(1)) receptor binding was altered in the postmortem dorsolateral prefrontal cortex (DLPFC) of individuals with schizophrenia (schizophrenia; n=47) compared to controls (n=43). The CB(1) receptor inverse agonist radioligand [(3)H]MePPEP was used...

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Autori principali: Jenko, Kimberly J., Hirvonen, Jussi, Henter, Ioline D., Anderson, Kacey B., Zoghbi, Sami S., Hyde, Thomas M., Deep-Soboslay, Amy, Innis, Robert B., Kleinman, Joel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463751/
https://ncbi.nlm.nih.gov/pubmed/22910406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2012.07.021
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