Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice

White adipose tissue (WAT) secretes adipokines, which critically regulate lipid metabolism. The present study investigated the effects of alcohol on adipokines and the mechanistic link between adipokine dysregulation and alcoholic fatty liver disease. Mice were fed alcohol for 2, 4, or 8 weeks to do...

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Hlavní autoři: Tan, Xiaobing, Sun, Xiuhua, Li, Qiong, Zhao, Yantao, Zhong, Wei, Sun, Xinguo, Jia, Wei, McClain, Craig J., Zhou, Zhanxiang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2012
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463622/
https://ncbi.nlm.nih.gov/pubmed/22841822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.013
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