Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice

White adipose tissue (WAT) secretes adipokines, which critically regulate lipid metabolism. The present study investigated the effects of alcohol on adipokines and the mechanistic link between adipokine dysregulation and alcoholic fatty liver disease. Mice were fed alcohol for 2, 4, or 8 weeks to do...

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Autors principals: Tan, Xiaobing, Sun, Xiuhua, Li, Qiong, Zhao, Yantao, Zhong, Wei, Sun, Xinguo, Jia, Wei, McClain, Craig J., Zhou, Zhanxiang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463622/
https://ncbi.nlm.nih.gov/pubmed/22841822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.013
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