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Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice

White adipose tissue (WAT) secretes adipokines, which critically regulate lipid metabolism. The present study investigated the effects of alcohol on adipokines and the mechanistic link between adipokine dysregulation and alcoholic fatty liver disease. Mice were fed alcohol for 2, 4, or 8 weeks to do...

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Main Authors: Tan, Xiaobing, Sun, Xiuhua, Li, Qiong, Zhao, Yantao, Zhong, Wei, Sun, Xinguo, Jia, Wei, McClain, Craig J., Zhou, Zhanxiang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463622/
https://ncbi.nlm.nih.gov/pubmed/22841822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.013
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