Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice

White adipose tissue (WAT) secretes adipokines, which critically regulate lipid metabolism. The present study investigated the effects of alcohol on adipokines and the mechanistic link between adipokine dysregulation and alcoholic fatty liver disease. Mice were fed alcohol for 2, 4, or 8 weeks to do...

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Bibliographic Details
Main Authors: Tan, Xiaobing, Sun, Xiuhua, Li, Qiong, Zhao, Yantao, Zhong, Wei, Sun, Xinguo, Jia, Wei, McClain, Craig J., Zhou, Zhanxiang
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2012
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463622/
https://ncbi.nlm.nih.gov/pubmed/22841822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.013
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