Leptin Deficiency Contributes to the Pathogenesis of Alcoholic Fatty Liver Disease in Mice

White adipose tissue (WAT) secretes adipokines, which critically regulate lipid metabolism. The present study investigated the effects of alcohol on adipokines and the mechanistic link between adipokine dysregulation and alcoholic fatty liver disease. Mice were fed alcohol for 2, 4, or 8 weeks to do...

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Detalhes bibliográficos
Main Authors: Tan, Xiaobing, Sun, Xiuhua, Li, Qiong, Zhao, Yantao, Zhong, Wei, Sun, Xinguo, Jia, Wei, McClain, Craig J., Zhou, Zhanxiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463622/
https://ncbi.nlm.nih.gov/pubmed/22841822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.013
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