Zinc deficiency mediates alcohol-induced apoptotic cell death in the liver of rats through activating ER and mitochondrial cell death pathways

Hepatic zinc deficiency has been well documented in alcoholic patients, but the mechanisms by which zinc deficiency mediates cell death have not been well defined. The objectives of this study were to determine whether alcohol perturbs subcellular zinc homeostasis and how organelle zinc depletion ma...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Sun, Qian, Zhong, Wei, Zhang, Wenliang, Li, Qiong, Sun, Xiuhua, Tan, Xiaobing, Sun, Xinguo, Dong, Daoyin, Zhou, Zhanxiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4421018/
https://ncbi.nlm.nih.gov/pubmed/25767260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00442.2014
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