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Anti-cancer activity of the cholesterol exporter ABCA1 gene
The ABCA1 protein mediates the transfer of cellular cholesterol across the plasma membrane to apolipoprotein A-I. Loss-of-function mutations in the ABCA1 gene induce Tangier disease and familial hypoalphalipoproteinemia, both cardio-vascular conditions characterized by abnormally low levels of serum...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462268/ https://ncbi.nlm.nih.gov/pubmed/22981231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.011 |
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