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Anti-cancer activity of the cholesterol exporter ABCA1 gene
The ABCA1 protein mediates the transfer of cellular cholesterol across the plasma membrane to apolipoprotein A-I. Loss-of-function mutations in the ABCA1 gene induce Tangier disease and familial hypoalphalipoproteinemia, both cardio-vascular conditions characterized by abnormally low levels of serum...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462268/ https://ncbi.nlm.nih.gov/pubmed/22981231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.08.011 |
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