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Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1

Recent epidemiologic data show that low serum cholesterol level as well as statin use is associated with a decreased risk of developing aggressive or advanced prostate cancer, suggesting a role for cholesterol in aggressive prostate cancer development. Intracellular cholesterol promotes prostate can...

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Detalhes bibliográficos
Main Authors: Lee, Byron H., Taylor, Margaret G., Robinet, Peggy, Smith, Jonathan D., Schweitzer, Jessica, Sehayek, Ephraim, Falzarano, Sara M., Magi-Galluzzi, Cristina, Klein, Eric A., Ting, Angela H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563867/
https://ncbi.nlm.nih.gov/pubmed/23233737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3128
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