Methylome-wide Sequencing Detects DNA Hypermethylation Distinguishing Indolent from Aggressive Prostate Cancer

A critical need in understanding the biology of prostate cancer is characterizing the molecular differences between indolent and aggressive cases. Because DNA methylation can capture the regulatory state of tumors, we analyzed differential methylation patterns genome-wide among benign prostatic tiss...

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Publicat a:Cell Rep
Autors principals: Bhasin, Jeffrey M., Lee, Byron H., Matkin, Lars, Taylor, Margaret G., Hu, Bo, Xu, Yaomin, Magi-Galluzzi, Cristina, Klein, Eric A., Ting, Angela H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684962/
https://ncbi.nlm.nih.gov/pubmed/26628371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.078
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