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Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex

Thrombin inactivation by heparin cofactor II (HCII) is accelerated by ternary complex formation with heparin. The novel active-site-labeled thrombins, [4′F]FPR-T and [6F]FFR-T, and the exosite I probe, Hir-(54–65)( [Formula: see text]), characterized thrombin exosite I and II interactions with HCII...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Verhamme, Ingrid M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461310/
https://ncbi.nlm.nih.gov/pubmed/22206940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.11.021
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