Načítá se...
Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism
The serine proteases sequentially activated to form a fibrin clot are inhibited primarily by members of the serpin family, which use a unique β-sheet expansion mechanism to trap and destroy their targets. Since the discovery that serpins were a family of serine protease inhibitors there has been con...
Uloženo v:
| Hlavní autoři: | , , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2002
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123213/ https://ncbi.nlm.nih.gov/pubmed/12169660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162232399 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|