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Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson’s disease

Mitochondrial oxidant stress is widely viewed as critical to pathogenesis in Parkinson’s disease. But the origins of this stress are poorly defined. One possibility is that it arises from the metabolic demands associated with regenerative activity. To test this hypothesis, neurons in the dorsal moto...

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Détails bibliographiques
Auteurs principaux: Goldberg, Joshua A., Guzman, Jaime N., Estep, Chad M., Ilijic, Ema, Kondapalli, Jyothisri, Sanchez-Padilla, Javier, Surmeier, D. James
Format: Artigo
Langue:Inglês
Publié: 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461271/
https://ncbi.nlm.nih.gov/pubmed/22941107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3209
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