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Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson’s disease

Mitochondrial oxidant stress is widely viewed as critical to pathogenesis in Parkinson’s disease. But the origins of this stress are poorly defined. One possibility is that it arises from the metabolic demands associated with regenerative activity. To test this hypothesis, neurons in the dorsal moto...

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Hlavní autoři: Goldberg, Joshua A., Guzman, Jaime N., Estep, Chad M., Ilijic, Ema, Kondapalli, Jyothisri, Sanchez-Padilla, Javier, Surmeier, D. James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461271/
https://ncbi.nlm.nih.gov/pubmed/22941107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3209
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