Identification, Characterization and Application of a G-Quadruplex Structured DNA Aptamer against Cancer Biomarker Protein Anterior Gradient Homolog 2

BACKGROUND: Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression. Clinical studies have shown that the AGR2 protein is overexpress...

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Detalhes bibliográficos
Main Authors: Wu, Jie, Wang, Chi, Li, Xilan, Song, Yanling, Wang, Wei, Li, Cong, Hu, Jia, Zhu, Zhi, Li, Jiuxing, Zhang, Weiyun, Lu, Zhongxian, Yang, Chaoyong James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460915/
https://ncbi.nlm.nih.gov/pubmed/23029506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046393
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