Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity

BACKGROUND: Glioblastoma is the most common and most lethal form of brain tumor in human. Unfortunately, there is still no effective therapy to this fatal disease and the median survival is generally less than one year from the time of diagnosis. Discovery of ligands that can bind specifically to th...

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Detalhes bibliográficos
Main Authors: Kang, Dezhi, Wang, Jiangjie, Zhang, Weiyun, Song, Yanling, Li, Xilan, Zou, Yuan, Zhu, Mingtao, Zhu, Zhi, Chen, Fuyong, Yang, Chaoyong James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462804/
https://ncbi.nlm.nih.gov/pubmed/23056171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042731
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