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Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity

BACKGROUND: Glioblastoma is the most common and most lethal form of brain tumor in human. Unfortunately, there is still no effective therapy to this fatal disease and the median survival is generally less than one year from the time of diagnosis. Discovery of ligands that can bind specifically to th...

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Autors principals: Kang, Dezhi, Wang, Jiangjie, Zhang, Weiyun, Song, Yanling, Li, Xilan, Zou, Yuan, Zhu, Mingtao, Zhu, Zhi, Chen, Fuyong, Yang, Chaoyong James
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462804/
https://ncbi.nlm.nih.gov/pubmed/23056171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042731
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