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Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13

Pks13 is a type I polyketide synthase involved in the final biosynthesis step of mycolic acids, virulence factors, and essential components of the Mycobacterium tuberculosis envelope. Here, we report the biochemical and structural characterization of a 52-kDa fragment containing the acyltransferase...

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Hlavní autoři: Bergeret, Fabien, Gavalda, Sabine, Chalut, Christian, Malaga, Wladimir, Quémard, Annaïk, Pedelacq, Jean-Denis, Daffé, Mamadou, Guilhot, Christophe, Mourey, Lionel, Bon, Cécile
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460465/
https://ncbi.nlm.nih.gov/pubmed/22825853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325639
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