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Mycobacterial polyketide-associated proteins are acyltransferases: Proof of principle with Mycobacterium tuberculosis PapA5

Mycobacterium tuberculosis (Mt) produces complex virulence-enhancing lipids with scaffolds consisting of phthiocerol and phthiodiolone dimycocerosate esters (PDIMs). Sequence analysis suggested that PapA5, a so-called polyketide-associated protein (Pap) encoded in the PDIM synthesis gene cluster, as...

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Detalhes bibliográficos
Main Authors: Onwueme, Kenolisa C., Ferreras, Julian A., Buglino, John, Lima, Christopher D., Quadri, Luis E. N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384794/
https://ncbi.nlm.nih.gov/pubmed/15070765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306928101
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