Biochemical and Structural Study of the Atypical Acyltransferase Domain from the Mycobacterial Polyketide Synthase Pks13

Pks13 is a type I polyketide synthase involved in the final biosynthesis step of mycolic acids, virulence factors, and essential components of the Mycobacterium tuberculosis envelope. Here, we report the biochemical and structural characterization of a 52-kDa fragment containing the acyltransferase...

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Detalles Bibliográficos
Autores principales: Bergeret, Fabien, Gavalda, Sabine, Chalut, Christian, Malaga, Wladimir, Quémard, Annaïk, Pedelacq, Jean-Denis, Daffé, Mamadou, Guilhot, Christophe, Mourey, Lionel, Bon, Cécile
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460465/
https://ncbi.nlm.nih.gov/pubmed/22825853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325639
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