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New WS9326A Congeners from Streptomyces sp. 9078 Inhibiting Brugia malayi asparaginyl-tRNA Synthetase

[Image: see text] Lymphatic filariasis is caused by the Brugia malayi parasite. Three new congeners of the depsipeptide WS9326A (1), WS9326C (2), WS9326D (3) and WS9326E (4), were isolated from Streptomyces sp. 9078 by using a B. malayi asparaginyl-tRNA synthetase (BmAsnRS) inhibition assay. WS9326D...

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Bibliografske podrobnosti
Main Authors: Yu, Zhiguo, Vodanovic-Jankovic, Sanja, Kron, Michael, Shen, Ben
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460372/
https://ncbi.nlm.nih.gov/pubmed/22967068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302298k
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