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New WS9326A Congeners from Streptomyces sp. 9078 Inhibiting Brugia malayi asparaginyl-tRNA Synthetase

[Image: see text] Lymphatic filariasis is caused by the Brugia malayi parasite. Three new congeners of the depsipeptide WS9326A (1), WS9326C (2), WS9326D (3) and WS9326E (4), were isolated from Streptomyces sp. 9078 by using a B. malayi asparaginyl-tRNA synthetase (BmAsnRS) inhibition assay. WS9326D...

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Detalhes bibliográficos
Main Authors: Yu, Zhiguo, Vodanovic-Jankovic, Sanja, Kron, Michael, Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460372/
https://ncbi.nlm.nih.gov/pubmed/22967068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302298k
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