Synthesis and Antibacterial Evaluation of a New Series of N-Alkyl-2-alkynyl/(E)-alkenyl-4-(1H)-quinolones

To gain further insight into the structural requirements of the aliphatic group at position 2 for their antimycobacterial activity, some N-alkyl-4-(1H)-quinolones bearing position 2 alkynyls with various chain length and triple bond positions were prepared and tested for in vitro antibacterial activ...

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Main Authors: Wube, Abraham, Guzman, Juan-David, Hüfner, Antje, Hochfellner, Christina, Blunder, Martina, Bauer, Rudolf, Gibbons, Simon, Bhakta, Sanjib, Bucar, Franz
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460366/
https://ncbi.nlm.nih.gov/pubmed/22777190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules17078217
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