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Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones

A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of...

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Hlavní autoři: Wube, Abraham A., Hüfner, Antje, Thomaschitz, Christina, Blunder, Martina, Kollroser, Manfred, Bauer, Rudolf, Bucar, Franz
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268452/
https://ncbi.nlm.nih.gov/pubmed/21106378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.10.060
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