Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria

In an effort to improve biological activities and to examine antimycobacterial-lipophilicity relationships of 2-[(1E)-alkenyl)]-4-(1H)-quinolones, we have synthesized a series of 30 quinolones by introducing several alkyl groups, an alkenyl and an alkynyl group at N-1. All synthetic compounds were f...

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Hlavní autoři: Wube, Abraham A., Bucar, Franz, Hochfellner, Christina, Blunder, Martina, Bauer, Rudolf, Hüfner, Antje
Médium: Artigo
Jazyk:Inglês
Vydáno: Editions Scientifiques Elsevier 2011
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096000/
https://ncbi.nlm.nih.gov/pubmed/21429630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.02.062
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