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Lymphatic endothelial cells - key players in regulation of tolerance and immunity

The lymphatic vasculature provides routes for dendritic cell and lymphocyte migration into and out of lymph nodes. Lymphatic endothelial cells (LEC) control these processes by expression of CCL21, sphingosine-1-phosphate, and adhesion molecules. LEC express MHC-I and MHC-II, but not costimulatory mo...

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Autori principali: Tewalt, Eric F., Cohen, Jarish N., Rouhani, Sherin J., Engelhard, Victor H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460259/
https://ncbi.nlm.nih.gov/pubmed/23060883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00305
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