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Lymphatic endothelial cells - key players in regulation of tolerance and immunity

The lymphatic vasculature provides routes for dendritic cell and lymphocyte migration into and out of lymph nodes. Lymphatic endothelial cells (LEC) control these processes by expression of CCL21, sphingosine-1-phosphate, and adhesion molecules. LEC express MHC-I and MHC-II, but not costimulatory mo...

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Bibliografiske detaljer
Main Authors: Tewalt, Eric F., Cohen, Jarish N., Rouhani, Sherin J., Engelhard, Victor H.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460259/
https://ncbi.nlm.nih.gov/pubmed/23060883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00305
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